Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709093 | 0.90 | MEN1 (0.48) | MEN1KMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL17709090 | 0.90 | MEN1 (0.48) | MEN1KMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL17709091 | 0.90 | MEN1 (0.48) | MEN1KMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL17709186 | 0.89 | MAOB (0.46) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL17709082 | 0.89 | CYP19A1 (0.51) | MEN1KMT2AUSP2MAOB | |
| SCHEMBL17709184 | 0.89 | MAOB (0.46) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL17709083 | 0.89 | CYP19A1 (0.51) | MEN1KMT2AUSP2MAOB | |
| SCHEMBL17709084 | 0.89 | CYP19A1 (0.51) | MEN1KMT2AUSP2MAOB | |
| SCHEMBL17709188 | 0.89 | MAOB (0.46) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL28516061 | 0.88 | MEN1 (0.53) | MEN1KMT2AUSP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912617-A | Substituted tricycles and methods of use | 艾伯维公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108349930-B | Substituted tricycles and methods of use | 艾伯维公司 | 2021-10-29 | — | — | CN | disclosed |