Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671279 | 0.88 | KRAS (0.55) | KRAS | |
| SCHEMBL29693129 | 0.87 | KRAS (0.54) | KRASPDE4B | |
| SCHEMBL24558375 | 0.87 | KRAS (0.54) | KRASPDE4B | |
| SCHEMBL28656532 | 0.85 | KRAS (0.54) | KRAS | |
| SCHEMBL28671533 | 0.84 | KRAS (0.53) | KRAS | |
| SCHEMBL28654351 | 0.83 | KRAS (0.55) | KRAS | |
| SCHEMBL28658835 | 0.83 | KRAS (0.48) | KRAS | |
| SCHEMBL28664628 | 0.81 | KRAS (0.46) | KRAS | |
| SCHEMBL28656559 | 0.81 | KRAS (0.43) | KRAS | |
| SCHEMBL28928617 | 0.80 | KRAS (0.55) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-A | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2021-10-15 | — | — | CN | disclosed |