Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22167123 | 1.00 | TRPV1 (0.43) | TRPV1GLACNR2PTGS1PGR | |
| Hydrochloric Acid SCHEMBL29411692 | 0.99 | TRPV1 (0.42) | TRPV1GLACNR2PTGS1PGR | |
| SCHEMBL31406759 | 0.89 | TRPV1 (0.47) | TRPV1GLAPTGS1PGRHTR1A | |
| SCHEMBL23970149 | 0.78 | TRPV1 (0.36) | TRPV1PTGS1PGRHTR1AADORA3 | |
| SCHEMBL22167126 | 0.78 | FDFT1 (0.52) | TRPV1GLAMAPT | |
| SCHEMBL22167122 | 0.77 | KMT2A (0.42) | MAPTKDM4E | |
| SCHEMBL28631147 | 0.77 | KMT2A (0.42) | MAPTKDM4E | |
| SCHEMBL8634136 | 0.76 | GLA (0.56) | GLACNR2MAPTC5AR1 | |
| Hydrochloric Acid SCHEMBL28646572 | 0.76 | KMT2A (0.41) | MAPTKDM4E | |
| SCHEMBL23970148 | 0.74 | TRPV1 (0.40) | TRPV1MAPTPTPN1BACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227036-B | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-11 | — | — | CN | disclosed |
| CN-113227036-A | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-08-06 | — | — | CN | disclosed |