SCHEMBL28652137

SCHEMBL28652137

CC(C)Oc1ccc(-c2nc(-c3ccc(COC(=O)C[C@H](N)C(=O)OCc4ccc(-c5noc(-c6ccc(OC(C)C)c(C#N)c6)n5)c(Cl)c4)cc3Cl)no2)cc1C#N

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 20/20 0.57
S1PR5 Q9H228 8/20 0.57
S1PR3 Q99500 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28638103 0.99 S1PR1 (0.56) S1PR1S1PR5S1PR3
SCHEMBL28643608 0.93 S1PR1 (0.57) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28652096 0.92 S1PR1 (0.57) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28643663 0.92 S1PR1 (0.60) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28645809 0.90 S1PR1 (0.57) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28640831 0.90 S1PR1 (0.56) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28643606 0.90 S1PR1 (0.59) S1PR1S1PR5S1PR3
SCHEMBL28643610 0.90 S1PR1 (0.64) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28652282 0.89 S1PR1 (0.55) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL28652098 0.89 S1PR1 (0.63) S1PR1S1PR5S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109956912-B Carboxylic acid compound containing diphenyl oxadiazole, preparation method and medical application thereof 中国医学科学院药物研究所 2021-10-22 CN disclosed