SCHEMBL28652298

SCHEMBL28652298

CCCCCc1ccc(-c2ccccc2)cc1F.OBO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.50
RARA P10276 2/20 0.50
RARG P13631 1/20 0.50
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
TYR P14679 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
ALOX5 P09917 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LIPG Q9Y5X9 1/20 0.41
TRPV1 Q8NER1 1/20 0.40
MGLL Q99685 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29287568 0.95 RARB (0.45) RARBRARARARGCYP3A4MAPT
SCHEMBL27800509 0.94 RARB (0.51) RARBRARARARGCYP3A4MAPT
SCHEMBL7789315 0.92 RARB (0.54) RARBRARARARGCYP3A4MAPT
SCHEMBL28347037 0.84 RARB (0.48) RARBRARARARGCYP3A4MAPT
SCHEMBL458899 0.82 RARB (0.41) RARBRARARARGMAPTLTB4R2
SCHEMBL23640788 0.82 TYR (0.61) RARBRARARARGCYP3A4MAPT
SCHEMBL9399298 0.81 RARB (0.62) RARBRARARARGCYP3A4MAPT
SCHEMBL9399744 0.81 RARB (0.62) RARBRARARARGCYP3A4MAPT
SCHEMBL9399722 0.80 RARB (0.65) RARBRARARARGCYP3A4MAPT
SCHEMBL9399112 0.80 RARB (0.57) RARBRARARARGCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110776927-B Isothiocyano fluorine-containing tetrabiphenyl liquid crystal compound, preparation method thereof, liquid crystal composition and application 武汉轻工大学 2021-09-17 CN disclosed
CN-110776927-A Isothiocyano fluorine-containing tetrabiphenyl liquid crystal compound, preparation method thereof, liquid crystal composition and application 武汉轻工大学 2020-02-11 CN disclosed