Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.70 |
| ▸ | LCK | P06239 | 18/20 | 0.70 |
| ▸ | EGFR | P00533 | 10/20 | 0.66 |
| ▸ | BTK | Q06187 | 14/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011519 | 1.00 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL28653136 | 1.00 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL21946758 | 0.91 | JAK3 (0.64) | JAK3LCKEGFRBTK | |
| SCHEMBL21946363 | 0.90 | JAK3 (0.72) | JAK3LCKEGFRBTK | |
| SCHEMBL30448210 | 0.90 | JAK3 (0.72) | JAK3LCKEGFRBTK | |
| SCHEMBL23484941 | 0.89 | JAK3 (0.71) | JAK3LCKEGFRBTK | |
| SCHEMBL28642037 | 0.87 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL30011291 | 0.87 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL28642039 | 0.87 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL21855199 | 0.87 | JAK3 (0.63) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113412259-A | Bifunctional compounds for the degradation of BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2021-09-17 | — | — | CN | disclosed |