Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404439 | 0.94 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL29935165 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19045411 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19030391 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19046307 | 0.91 | IRAK4 (0.88) | IRAK4 | |
| SCHEMBL20594241 | 0.90 | IRAK4 (0.87) | IRAK4 | |
| SCHEMBL20594263 | 0.90 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL19030675 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL19030417 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL20594496 | 0.89 | IRAK4 (0.85) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473498-B | Pyrazolo [1,5a ] pyrimidine derivatives as IRAK4 modulators | 豪夫迈·罗氏有限公司 | 2021-11-02 | — | — | CN | disclosed |