SCHEMBL28654448

SCHEMBL28654448

CC[Si](CC)(CC)CCc1ccc(C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
IDO1 P14902 1/20 0.41
HRH3 Q9Y5N1 1/20 0.39
KCNH2 Q12809 1/20 0.39
IGF1R P08069 1/20 0.38
ALOX15 P16050 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
AGXT P21549 2/20 0.37
TDP1 Q9NUW8 2/20 0.36
ACHE P22303 1/20 0.36
CHKA P35790 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28659472 0.80 TAAR1 (0.47) TAAR1IDO1ALDH1A1KMT2AL3MBTL1
SCHEMBL28669826 0.79 TDP1 (0.48) CYP2A6TAAR1KCNH2ALOX15SMN1; SMN2
SCHEMBL14078071 0.78 CYP1A2 (0.45) CYP1A2CYP2A6TAAR1IDO1HRH3
SCHEMBL28660275 0.77 CYP11B1 (0.33) ALDH1A1MEN1KMT2A
SCHEMBL28660351 0.77 KCNH2 (0.46) KCNH2NPC1RAB9A
SCHEMBL16335308 0.77 TAAR1 (0.53) TAAR1IDO1SMN1; SMN2KMT2A
SCHEMBL28659125 0.77 TAAR1 (0.53) TAAR1IDO1KCNH2
SCHEMBL24602755 0.76 CYP1A2 (0.52) CYP1A2CYP2A6TAAR1IDO1HRH3
SCHEMBL988079 0.76 IDO1 (0.44) CYP1A2CYP2A6TAAR1IDO1HRH3
SCHEMBL28672310 0.75 TAAR1 (0.55) TAAR1IDO1HRH3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717209-A Synthesis method of alkyl silicon compound 南通大学 2021-11-30 CN disclosed