Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139506 | 1.00 | CRBN (0.60) | CRBNMAPK14HDAC3SMYD3HDAC1 | |
| SCHEMBL20774011 | 0.83 | CRBN (0.60) | CRBNMAPK14HDAC3SMYD3L3MBTL1 | |
| SCHEMBL30800736 | 0.83 | CRBN (0.60) | CRBNMAPK14HDAC3SMYD3L3MBTL1 | |
| SCHEMBL28657524 | 0.83 | CRBN (0.56) | CRBNSMYD3GAAMAPTSMN1; SMN2 | |
| SCHEMBL5316057 | 0.82 | CRBN (0.81) | CRBNHDAC3SMYD3HDAC1EPHX2 | |
| SCHEMBL28669417 | 0.80 | HDAC3 (0.44) | CRBNMAPK14HDAC3SMYD3KDM4E | |
| SCHEMBL31139519 | 0.80 | HDAC3 (0.44) | CRBNMAPK14HDAC3SMYD3KDM4E | |
| SCHEMBL23175457 | 0.76 | CRBN (1.00) | CRBNMAPK14SMYD3EPHX2 | |
| SCHEMBL29899649 | 0.76 | CRBN (1.00) | CRBNMAPK14SMYD3EPHX2 | |
| SCHEMBL20773006 | 0.74 | BCL6 (0.57) | MAPK14KDM4EGAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113557235-A | Heterocyclic compounds for use in medical therapy | C4医药公司 | 2021-10-26 | — | — | CN | disclosed |