SCHEMBL28654963

SCHEMBL28654963

O=C(O)CC1CCC([N+](=O)[O-])CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.43
ENPEP Q07075 1/20 0.43
SLC6A12 P48065 5/20 0.41
SLC6A11 P48066 5/20 0.41
SLC6A13 Q9NSD5 5/20 0.41
SLC6A1 P30531 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA1 P14867 1/20 0.41
GABRR1 P24046 1/20 0.41
GABRA4 P48169 1/20 0.41
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FFAR4 Q5NUL3 3/20 0.35
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
BLM P54132 1/20 0.33
HBB P68871 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13245814 1.00 ANPEP (0.43) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL11797678 0.91 ANPEP (0.41) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL1493230 0.81 ANPEP (0.56) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL431287 0.81 ANPEP (0.56) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL24483431 0.81 ANPEP (0.56) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL24197646 0.81 ANPEP (0.56) ANPEPENPEPSLC6A12SLC6A11SLC6A13
SCHEMBL74792 0.81
SCHEMBL28300354 0.81 ANPEP (0.56) ANPEPENPEPSLC6A12SLC6A11SLC6A13
Hydrochloric Acid SCHEMBL8681566 0.78
SCHEMBL15771317 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493399-A Preparation method for converting configuration of key intermediate of cariprazine 北京万全德众医药生物技术有限公司 2021-10-12 CN claimed
CN-113493399-A Preparation method for converting configuration of key intermediate of cariprazine 北京万全德众医药生物技术有限公司 2021-10-12 CN disclosed