Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212446 | 1.00 | CARM1 (0.57) | CARM1PRMT5WDR77MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18205181 | 0.98 | CARM1 (0.56) | CARM1PRMT5WDR77MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18205182 | 0.98 | CARM1 (0.56) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL21020831 | 0.90 | CARM1 (0.59) | CARM1PRMT5WDR77MAOAMAOB | |
| SCHEMBL27478638 | 0.90 | CARM1 (0.59) | CARM1PRMT5WDR77MAOAMAOB | |
| SCHEMBL18212435 | 0.87 | CARM1 (0.51) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL3418321 | 0.86 | CARM1 (0.60) | CARM1PRMT5WDR77MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18205134 | 0.85 | CARM1 (0.50) | CARM1PRMT5WDR77MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18205133 | 0.85 | CARM1 (0.50) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL24306794 | 0.85 | CARM1 (0.61) | CARM1PRMT5WDR77MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |