Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680310 | 0.93 | TMPRSS2 (0.43) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL28675704 | 0.90 | TMPRSS2 (0.44) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL31239297 | 0.88 | TMPRSS2 (0.45) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL31239313 | 0.86 | TMPRSS2 (0.41) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL24790478 | 0.85 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL31239303 | 0.85 | TMPRSS2 (0.42) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL23960034 | 0.85 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL30516176 | 0.84 | TMPRSS2 (0.44) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL31239300 | 0.84 | TMPRSS2 (0.41) | TMPRSS2POLRMT | |
| SCHEMBL30516180 | 0.84 | TMPRSS2 (0.41) | TMPRSS2POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027040-A | Nucleoside compound for treating coronavirus infection and application thereof | 南方科技大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117964624-A | Nucleoside compound with effect of treating viral infection and application thereof | 南方科技大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117777141-A | Nucleoside compound for resisting virus infection and application thereof | 南方科技大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-116370479-B | Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection | 南方科技大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-113735862-B | Nucleoside compound for treating viral infection and application thereof | 南方科技大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-116874490-A | Compound ATV014 or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof | 南方科技大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-116370479-A | Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection | 南方科技大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113754665-B | Preparation method of nucleoside compound | 南方科技大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113754665-A | Preparation method of nucleoside compound | 南方科技大学 | 2021-12-07 | — | — | CN | disclosed |