SCHEMBL28655868

SCHEMBL28655868

C[C@@H](N)C(=O)N[C@H]1CCN(C)C1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
XIAP P98170 3/20 0.41
KDM4E B2RXH2 1/20 0.40
SSTR4 P31391 7/20 0.37
SSTR1 P30872 5/20 0.37
SMYD3 Q9H7B4 1/20 0.37
HRH2 P25021 1/20 0.36
HRH1 P35367 1/20 0.36
KDM5A P29375 2/20 0.35
FPR2 P25090 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28671243 1.00 XIAP (0.41) XIAPKDM4ESSTR4SSTR1SMYD3
SCHEMBL21835882 0.89 KDM4E (0.49) XIAPKDM4ESSTR4SMYD3FPR2
SCHEMBL13321380 0.89 KDM4E (0.49) XIAPKDM4ESSTR4SMYD3FPR2
SCHEMBL28928688 0.87 XIAP (0.42) XIAPKDM4ESSTR4SSTR1HRH2
SCHEMBL28659424 0.87 XIAP (0.42) XIAPKDM4ESSTR4SSTR1HRH2
SCHEMBL16078081 0.86 KDM5A (0.45) KDM4ESSTR4SSTR1KDM5AFPR2
SCHEMBL13192995 0.86 KDM5A (0.45) KDM4ESSTR4SSTR1KDM5AFPR2
SCHEMBL18347953 0.86 KDM5A (0.45) KDM4ESSTR4SSTR1KDM5AFPR2
SCHEMBL7457423 0.80 XIAP (0.42) XIAPSMYD3KDM5A
SCHEMBL355760 0.80 CHRNB4 (0.48) KDM4ESSTR4SSTR1CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511213-B Immunomodulator 成都先导药物开发股份有限公司 2021-10-19 CN disclosed
CN-110511213-A A kind of immunomodulator CHENGDU HITGEN DEV CO LTD 2019-11-29 CN disclosed