SCHEMBL28655920

SCHEMBL28655920

N#CC(Cl)(Cl)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
CYP1A2 P05177 3/20 0.45
CYP1A1 P04798 2/20 0.45
CYP1B1 Q16678 2/20 0.45
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
KCNA3 P22001 1/20 0.37
FDPS P14324 1/20 0.36
CALM1 P0DP23 1/20 0.36
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
OPRM1 P35372 1/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27810843 0.82 ATM (0.46) ATMCYP1A2CYP1A1CYP1B1SLC6A2
SCHEMBL28619495 0.80 SLC6A4 (0.47) CYP1A2SLC6A2TAAR1ALDH1A1CYP2C9
SCHEMBL28425100 0.78 CYP1A2 (0.47) ATMCYP1A2CYP1A1CYP1B1SLC6A2
SCHEMBL11566623 0.78 IDO1 (0.38) TAAR1ALDH1A1LMNAMAOBESR1
SCHEMBL11568801 0.78 ESR1 (0.36) CYP1A2CYP1A1CYP1B1ESR1ESR2
SCHEMBL10891578 0.78 SLC6A2 (0.48) ATMCYP1A2CYP1A1CYP1B1SLC6A2
SCHEMBL11386011 0.77 SMN1; SMN2 (0.42) CYP1A2CYP1A1CYP1B1SLC6A2TAAR1
SCHEMBL28290835 0.76 ATM (0.48) ATMCYP1A2CYP1A1CYP1B1SLC6A2
SCHEMBL11830117 0.74 CYP1A2 (0.52) ATMCYP1A2CYP1A1CYP1B1SLC6A2
SCHEMBL2375732 0.73 SLC6A2 (0.46) ATMCYP1A2SLC6A2TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-215028650-U Reaction kettle for preparing dichlorobenzyl cyanide 浙江东海新材料科技股份有限公司 2021-12-07 CN claimed