Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.55 |
| ▸ | IL6 | P05231 | 10/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26354284 | 0.92 | TLR7 (0.48) | TLR7IL6BCHEACHETLR8 | |
| SCHEMBL26359789 | 0.91 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL26354074 | 0.90 | TLR7 (0.66) | TLR7IL6TLR8 | |
| SCHEMBL26347756 | 0.90 | TLR7 (0.60) | TLR7IL6TLR8 | |
| SCHEMBL26347721 | 0.88 | TLR7 (0.64) | TLR7IL6TLR8 | |
| SCHEMBL26358175 | 0.87 | TLR7 (0.59) | TLR7IL6TLR8 | |
| SCHEMBL29034558 | 0.86 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL29475652 | 0.85 | TLR7 (0.65) | TLR7IL6TLR8 | |
| SCHEMBL22347092 | 0.85 | TLR7 (0.65) | TLR7IL6TLR8 | |
| SCHEMBL26347251 | 0.85 | TLR7 (0.59) | TLR7IL6TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4199968-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | Ambrx, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040596-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |