Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 20/20 | 0.68 |
| ▸ | EEF2K | O00418 | 1/20 | 0.64 |
| ▸ | MARK3 | P27448 | 1/20 | 0.64 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
| ▸ | BCL6 | P41182 | 1/20 | 0.64 |
| ▸ | NEK4 | P51957 | 1/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.64 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.64 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.64 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.64 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.64 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.64 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.64 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.64 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802262 | 0.92 | MCL1 (0.57) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL28658541 | 0.90 | MCL1 (0.55) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL28926846 | 0.89 | MCL1 (0.74) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL19615336 | 0.85 | MCL1 (0.62) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL24745337 | 0.84 | MCL1 (0.68) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL30000669 | 0.84 | MCL1 (0.68) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL19616061 | 0.84 | MCL1 (0.73) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL19615293 | 0.84 | MCL1 (0.70) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL19618991 | 0.83 | MCL1 (0.70) | MCL1EEF2KMARK3AXLBCL6 | |
| SCHEMBL28658588 | 0.83 | MCL1 (0.58) | MCL1EEF2KMARK3AXLBCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715632-B | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2021-10-26 | — | — | CN | disclosed |