Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644058 | 0.81 | CNR2 (0.39) | ACHEMAPTMEN1KMT2ACNR1 | |
| SCHEMBL27228071 | 0.78 | CNR2 (0.39) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL2144860 | 0.78 | CNR2 (0.39) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL2144335 | 0.77 | CNR2 (0.38) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL30284921 | 0.77 | CNR2 (0.38) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL29644076 | 0.76 | CNR2 (0.38) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL2144082 | 0.76 | ELANE (0.41) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL3705619 | 0.76 | CNR2 (0.37) | HTTACHEMAPTMEN1KMT2A | |
| SCHEMBL2470918 | 0.75 | CNR2 (0.45) | ACHEMAPTMEN1KMT2ACNR1 | |
| SCHEMBL3517141 | 0.75 | CNR2 (0.45) | ACHEMAPTMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710667-A | Fused cyclic pyrimidinone derivatives for the treatment of HBV infection or HBV induced diseases | 爱尔兰詹森科学公司 | 2021-11-26 | — | — | CN | disclosed |