Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656739 | 1.00 | IDH1 (0.78) | IDH1 | |
| SCHEMBL19700940 | 1.00 | IDH1 (0.78) | IDH1 | |
| SCHEMBL19700762 | 0.95 | IDH1 (0.78) | IDH1 | |
| SCHEMBL19700764 | 0.94 | IDH1 (0.80) | IDH1 | |
| SCHEMBL21378547 | 0.90 | IDH1 (0.84) | IDH1 | |
| SCHEMBL21378546 | 0.90 | IDH1 (0.84) | IDH1 | |
| SCHEMBL21378544 | 0.90 | IDH1 (0.84) | IDH1 | |
| SCHEMBL21378548 | 0.88 | IDH1 (0.81) | IDH1 | |
| SCHEMBL19700742 | 0.88 | IDH1 (0.81) | IDH1 | |
| SCHEMBL21378549 | 0.88 | IDH1 (0.81) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311863-B | Mutant IDH1 inhibitors | 伊莱利利公司 | 2021-10-29 | — | — | CN | disclosed |