SCHEMBL2865735

SCHEMBL2865735

CC(C)(OOC(C)(C)c1cccc(C(C)(C)OOC(C)(C)c2ccccc2)c1)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.81
ALDH1A1 P00352 3/20 0.54
ALOX15 P16050 1/20 0.54
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
TAAR1 Q96RJ0 1/20 0.38
CYP3A4 P08684 1/20 0.37
KCNN4 O15554 4/20 0.36
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
TACR1 P25103 1/20 0.35
TSHR P16473 2/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10346259 0.94 MAPK1 (0.71) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL10593256 0.94 MAPK1 (0.71) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL6534628 0.93 MAPK1 (0.85) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL15450 0.90 MAPK1 (1.00) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL27506519 0.90 MAPK1 (1.00) MAPK1ALDH1A1ALOX15ESR1ESR2
Benzene SCHEMBL25312146 0.90 MAPK1 (1.00) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL8939342 0.90 MAPK1 (1.00) MAPK1ALDH1A1ALOX15ESR1ESR2
Hydrogen Peroxide SCHEMBL22163808 0.87 MAPK1 (0.94) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL30089546 0.87 MAPK1 (0.94) MAPK1ALDH1A1ALOX15ESR1ESR2
Ethane SCHEMBL28682771 0.87 MAPK1 (0.94) MAPK1ALDH1A1ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US claimed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US claimed
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
EP-1854822-B1 Optical devices made from radiation curable fluorinated compositions ENABLENCE TECHNOLOGIES USA INC (CA) 2010-06-23 EP disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
EP-1854822-A1 Optical devices made from radiation curable fluorinated compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-14 EP disclosed
EP-1203031-B1 OPTICAL DEVICES MADE FROM RADIATION CURABLE FLUORINATED COMPOSITIONS DU PONT (US) 2007-10-24 EP disclosed
US-4523983-A Reactive plastisol dispersion W. R. GRACE & CO. (US) 1985-06-18 US disclosed
EP-0130389-A2 One component thermoset composition W.R. GRACE & CO. (US) 1985-01-09 EP disclosed
EP-0124812-A1 Reactive plastisol dispersion W.R. GRACE & CO. (US) 1984-11-14 EP disclosed
EP-0124808-A1 Reactive plastisol dispersion W.R. Grace & Co.-Conn. (US) 1984-11-14 EP disclosed
US-4463128-A Reactive plastisol dispersion W. R. GRACE & CO. (US) 1984-07-31 US disclosed
US-4444806-A Process for forming an epoxy-acrylate coating W. R. GRACE & CO. (US) 1984-04-24 US disclosed
US-4443495-A ETHYLENICALLY UNSATURATED COMPOUND AND A POLYTHIOL, SCREEN PRINTABLE W. R. GRACE & CO. (US) 1984-04-17 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed