Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236336 | 0.87 | S1PR3 (0.41) | S1PR3TSHRPPARASMN1; SMN2TTR | |
| SCHEMBL14542266 | 0.85 | S1PR3 (0.65) | S1PR3TSHRHTR2BALDH1A1HTT | |
| SCHEMBL14541876 | 0.85 | S1PR3 (0.65) | S1PR3TSHRHTR2BALDH1A1HTT | |
| SCHEMBL9219685 | 0.85 | S1PR3 (0.65) | S1PR3TSHRHTR2BALDH1A1HTT | |
| SCHEMBL14528304 | 0.85 | S1PR3 (0.65) | S1PR3TSHRHTR2BALDH1A1HTT | |
| SCHEMBL30184755 | 0.82 | HTT (0.46) | S1PR3TSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL1778964 | 0.82 | KDM4E (0.46) | S1PR3TSHRSMN1; SMN2CYP1A2ADRA1A | |
| SCHEMBL564008 | 0.81 | S1PR3 (0.41) | S1PR3TSHRPPARASMN1; SMN2TTR | |
| SCHEMBL14915169 | 0.81 | S1PR3 (0.41) | S1PR3TSHRPPARASMN1; SMN2TTR | |
| SCHEMBL9935430 | 0.81 | S1PR3 (0.41) | S1PR3TSHRPPARASMN1; SMN2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |