Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 6/20 | 0.42 |
| ▸ | XIAP | P98170 | 4/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371245 | 1.00 | HTT (0.42) | HTTBIRC2XIAPBIRC3ALDH1A1 | |
| SCHEMBL27145258 | 1.00 | HTT (0.42) | HTTBIRC2XIAPBIRC3ALDH1A1 | |
| SCHEMBL16990979 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL15799374 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL16807540 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL13164408 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL31039889 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL29547949 | 0.89 | BIRC2 (0.44) | BIRC2XIAPBIRC3 | |
| SCHEMBL14790334 | 0.87 | BIRC2 (0.49) | BIRC2XIAPBIRC3 | |
| SCHEMBL17457784 | 0.87 | XIAP (0.43) | BIRC2XIAPBIRC3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-A | Bifunctional compounds for the degradation of BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2021-09-17 | — | — | CN | disclosed |