Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.72 |
| ▸ | LCK | P06239 | 18/20 | 0.72 |
| ▸ | BTK | Q06187 | 7/20 | 0.72 |
| ▸ | EGFR | P00533 | 10/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658114 | 1.00 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL21855324 | 0.90 | JAK3 (0.75) | JAK3LCKBTKEGFR | |
| SCHEMBL31039921 | 0.90 | JAK3 (0.75) | JAK3LCKBTKEGFR | |
| SCHEMBL21855319 | 0.90 | JAK3 (0.75) | JAK3LCKBTKEGFR | |
| SCHEMBL29264636 | 0.90 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL30012225 | 0.90 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL21946810 | 0.90 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL23459433 | 0.89 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL23459432 | 0.89 | JAK3 (0.72) | JAK3LCKBTKEGFR | |
| SCHEMBL29872252 | 0.89 | JAK3 (0.72) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-A | Bifunctional compounds for the degradation of BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2021-09-17 | — | — | CN | disclosed |