Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 19/20 | 0.66 |
| ▸ | ALB | P02768 | 2/20 | 0.60 |
| ▸ | BCL2 | P10415 | 2/20 | 0.54 |
| ▸ | PMAIP1 | Q13794 | 5/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAD | Q92934 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645744 | 0.95 | MCL1 (0.67) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL19634872 | 0.94 | MCL1 (0.59) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28642652 | 0.91 | MCL1 (0.68) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28925503 | 0.91 | MCL1 (0.60) | MCL1ALBBCL2PMAIP1 | |
| SCHEMBL19635901 | 0.90 | MCL1 (0.60) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28642283 | 0.89 | MCL1 (0.55) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28637645 | 0.89 | MCL1 (0.57) | MCL1ALBBCL2PMAIP1 | |
| SCHEMBL19635777 | 0.89 | MCL1 (0.60) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28652809 | 0.89 | MCL1 (0.58) | MCL1ALBBCL2PMAIP1BCL2L1 | |
| SCHEMBL28643135 | 0.88 | MCL1 (0.63) | MCL1ALBBCL2PMAIP1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715632-B | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2021-10-26 | — | — | CN | disclosed |