Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658311 | 1.00 | BUB1 (0.34) | BUB1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL24248752 | 1.00 | BUB1 (0.34) | BUB1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL30299945 | 1.00 | BUB1 (0.34) | BUB1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL25092592 | 1.00 | BUB1 (0.34) | BUB1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL22324107 | 0.80 | — | — | |
| SCHEMBL22324331 | 0.80 | — | — | |
| SCHEMBL22324276 | 0.80 | — | — | |
| SCHEMBL29461664 | 0.77 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL29461706 | 0.77 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL20705097 | 0.76 | BUB1 (0.40) | BUB1CHRM2CHRM1CHRM3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677344-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113661162-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2021-11-16 | — | — | CN | disclosed |