Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.61 |
| ▸ | FAP | Q12884 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PEPD | P12955 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798445 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL20681629 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL20681631 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13049763 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8258468 | 0.86 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL7590167 | 0.84 | ACE (0.49) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL7590163 | 0.84 | ACE (0.49) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8232124 | 0.83 | DPP4 (0.57) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL12340713 | 0.83 | DPP4 (0.57) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8725597 | 0.82 | ACE (0.53) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677399-A | Bivalent antagonists of inhibitor of apoptosis proteins | 和博医药有限公司 | 2021-11-19 | — | — | CN | disclosed |