Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494546 | 0.92 | PDGFRB (0.63) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL2735804 | 0.82 | ATM (0.56) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL1428560 | 0.80 | PDGFRB (0.72) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL2717168 | 0.79 | PDGFRB (0.70) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL5827810 | 0.77 | PDGFRB (0.72) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL6866887 | 0.76 | PDGFRB (1.00) | PDGFRBPDGFRATSHRFLT3MEN1 | |
| SCHEMBL16756061 | 0.75 | KDM4E (0.80) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL18768548 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL2729934 | 0.75 | PDGFRB (0.79) | KDM4EALDH1A1PDGFRBPDGFRAHPGD | |
| SCHEMBL335235 | 0.75 | PDGFRB (0.79) | KDM4EALDH1A1PDGFRBPDGFRAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |