Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280817 | 0.82 | KDM4E (0.59) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL14119038 | 0.82 | MEN1 (0.46) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL2272671 | 0.82 | MEN1 (0.62) | MEN1KMT2APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL28665614 | 0.78 | MEN1 (0.44) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL28662112 | 0.78 | MEN1 (0.43) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL28660747 | 0.77 | MEN1 (0.43) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL10383765 | 0.77 | FOLH1 (0.71) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL20140769 | 0.76 | FOLH1 (0.48) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL28659959 | 0.76 | MEN1 (0.44) | MEN1KMT2APOLBFOLH1KDM4E | |
| SCHEMBL28676414 | 0.76 | MEN1 (0.42) | MEN1KMT2APOLBFOLH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |