Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.97 |
| ▸ | PKM | P14618 | 1/20 | 0.97 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095808 | 1.00 | MAPT (0.97) | MAPTPKMTACR1TSHRALDH1A1 | |
| SCHEMBL3209495 | 1.00 | MAPT (0.97) | MAPTPKMTACR1TSHRALDH1A1 | |
| SCHEMBL3007095 | 1.00 | MAPT (0.97) | MAPTPKMTACR1TSHRALDH1A1 | |
| SCHEMBL1105979 | 1.00 | MAPT (0.97) | MAPTPKMTACR1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1097377 | 0.99 | MAPT (1.00) | MAPTPKMTACR1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28668754 | 0.99 | MAPT (1.00) | MAPTPKMTACR1TSHRALDH1A1 | |
| SCHEMBL19483128 | 0.89 | MAPT (0.79) | MAPTPKMTSHRALDH1A1HTT | |
| SCHEMBL17486606 | 0.89 | MAPT (0.79) | MAPTPKMTSHRALDH1A1HTT | |
| SCHEMBL6029174 | 0.89 | MAPT (0.79) | MAPTPKMTSHRALDH1A1HTT | |
| SCHEMBL17485269 | 0.89 | MAPT (0.79) | MAPTPKMTSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113038990-A | Novel amino-pyrimidinone-piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-06-25 | — | — | CN | disclosed |