Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.52 |
| ▸ | IL6 | P05231 | 10/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26354522 | 1.00 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL26347448 | 0.92 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL26347376 | 0.92 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL29034568 | 0.92 | TLR7 (0.55) | TLR7IL6TLR8 | |
| SCHEMBL26356048 | 0.91 | TLR7 (0.53) | TLR7IL6TLR8 | |
| SCHEMBL26356991 | 0.90 | TLR7 (0.50) | TLR7IL6 | |
| SCHEMBL26360242 | 0.90 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL26347360 | 0.90 | TLR7 (0.52) | TLR7IL6TLR8 | |
| SCHEMBL26347339 | 0.89 | TLR7 (0.52) | TLR7IL6 | |
| SCHEMBL28656515 | 0.89 | TLR7 (0.56) | TLR7IL6TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |