Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994458 | 1.00 | POLB (0.61) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL124227 | 1.00 | POLB (0.61) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL3387568 | 0.97 | POLB (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL24606366 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL24383487 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL23946129 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL24383312 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL24202656 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL23946128 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 | |
| SCHEMBL22790899 | 0.95 | MAPT (0.64) | POLBEPHX1EPHX2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113621175-B | Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof | 中国科学院化学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-113621175-A | Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof | 中国科学院化学研究所 | 2021-11-09 | — | — | CN | disclosed |