Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 20/20 | 0.88 |
| ▸ | TNKS2 | Q9H2K2 | 20/20 | 0.88 |
| ▸ | PARP1 | P09874 | 1/20 | 0.78 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.78 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20955148 | 0.93 | TNKS (1.00) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954737 | 0.92 | TNKS (1.00) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL22058610 | 0.90 | TNKS (0.86) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL23289921 | 0.89 | TNKS (0.84) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954825 | 0.89 | TNKS (0.84) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954842 | 0.89 | TNKS (0.84) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954776 | 0.89 | TNKS (0.84) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954765 | 0.88 | TNKS (0.81) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20955136 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP1PARP10PARP2 | |
| SCHEMBL20954738 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP1PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023315-B | Novel compound or pharmacologically acceptable salt thereof | 国立研究开发法人理化学研究所 | 2021-11-12 | — | — | CN | claimed |
| CN-110023315-B | Novel compound or pharmacologically acceptable salt thereof | 国立研究开发法人理化学研究所 | 2021-11-12 | — | — | CN | disclosed |