Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850805 | 0.89 | GAA (0.63) | SMN1; SMN2LMNAMAPTMAPK1GAA | |
| SCHEMBL23926498 | 0.88 | MAPT (0.55) | SMN1; SMN2LMNAMAPTMAPK1GAA | |
| SCHEMBL32933259 | 0.88 | MAPT (0.55) | SMN1; SMN2LMNAMAPTMAPK1GAA | |
| SCHEMBL28651411 | 0.87 | MAPT (0.49) | SMN1; SMN2LMNAMAPTMAPK1GAA | |
| SCHEMBL13778132 | 0.82 | MAPT (0.53) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL3313887 | 0.80 | GAA (0.72) | SMN1; SMN2LMNAMAPTMAPK1GAA | |
| SCHEMBL29554269 | 0.79 | MAPT (0.40) | MAPTMAPK1GAAALDH1A1GFER | |
| SCHEMBL31485111 | 0.79 | KDM4E (0.50) | SMN1; SMN2MAPTMAPK1GAAALDH1A1 | |
| SCHEMBL1934039 | 0.79 | MAPT (0.40) | MAPTMAPK1GAAALDH1A1GFER | |
| SCHEMBL15286142 | 0.79 | POLB (0.53) | SMN1; SMN2LMNAMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864081-B | FGFR4 inhibitor and preparation and application thereof | 南京圣和药业股份有限公司 | 2021-11-23 | — | — | CN | disclosed |