Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.50 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 5/20 | 0.47 |
| ▸ | PAK3 | O75914 | 1/20 | 0.47 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 4/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065156 | 1.00 | IGF1R (0.50) | IGF1RNEK1NTRK1PAK1PAK3 | |
| SCHEMBL14723359 | 0.91 | PAK1 (0.54) | IGF1RNEK1NTRK1PAK1PAK3 | |
| SCHEMBL1164508 | 0.84 | IGF1R (0.65) | IGF1RNEK1NTRK1PAK1PAK4 | |
| SCHEMBL24065121 | 0.84 | IGF1R (0.51) | IGF1RNEK1NTRK1PAK1PAK4 | |
| SCHEMBL14723558 | 0.82 | PAK1 (0.52) | IGF1RNEK1NTRK1PAK1PAK3 | |
| SCHEMBL14723204 | 0.82 | IGF1R (0.60) | IGF1RNEK1PAK1PAK4 | |
| SCHEMBL14723540 | 0.82 | IGF1R (0.60) | IGF1RNEK1PAK1PAK3PAK2 | |
| SCHEMBL24065066 | 0.78 | PAK1 (0.50) | IGF1RNEK1NTRK1PAK1PAK3 | |
| SCHEMBL24065100 | 0.77 | IGF1R (0.52) | IGF1RNEK1PAK1PAK4 | |
| SCHEMBL14723217 | 0.77 | IGF1R (0.52) | IGF1RNEK1PAK1PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710663-A | Modulators of MYC family proto-oncogene proteins | 纳罗医疗公司 | 2021-11-26 | — | — | CN | disclosed |