Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.78 |
| ▸ | THRB | P10828 | 8/20 | 0.78 |
| ▸ | BLM | P54132 | 7/20 | 0.78 |
| ▸ | RECQL | P46063 | 6/20 | 0.78 |
| ▸ | TOP2A | P11388 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 4/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.78 |
| ▸ | FYN | P06241 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603307 | 0.93 | MEN1 (0.77) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL43830 | 0.93 | MEN1 (0.83) | MEN1KMT2ATHRBBLMRECQL | |
| Water SCHEMBL4954979 | 0.92 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL17705921 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL17899511 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL2369231 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL12022391 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL20548043 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL22970097 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL3839149 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384283-B | Therapeutic heterocyclic compounds | 吉利德科学公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-115198018-A | Method for classifying patients with solid cancer | 法国国家卫生及研究医学协会 | 2022-10-18 | — | — | CN | disclosed |
| CN-108727407-B | Novel benzodiazepine derivatives | 伊缪诺金公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113631196-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-113302204-A | Dosing regimen of anti-TIGIT antibodies for treatment of cancer | 默沙东公司 | 2021-08-24 | — | — | CN | disclosed |