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SCHEMBL28664973

SCHEMBL28664973

Cn1nc(C(C)(C)NC(=O)[C@H]2C[C@@H]3CN(C(=O)O)C[C@@H]3C2)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 20/20 0.59
▸ SSTR1 P30872 8/20 0.59
▸ SSTR2 P30874 6/20 0.57
▸ SSTR3 P32745 6/20 0.57
▸ SSTR5 P35346 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28664974 1.00 SSTR4 (0.59) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL24048622 0.88 SSTR4 (0.55) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL24048319 0.85 SSTR4 (0.73) SSTR4SSTR1SSTR2SSTR3SSTR5
Formic Acid SCHEMBL30448780 0.82 SSTR4 (0.68) SSTR4SSTR1SSTR2SSTR3SSTR5
Formic Acid SCHEMBL28676916 0.82 SSTR4 (0.68) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL22015267 0.78 SSTR4 (0.69) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL16252697 0.74 SSTR4 (1.00) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL19724522 0.74 SSTR4 (1.00) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL19724649 0.74 SSTR4 (1.00) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL19724403 0.73 SSTR4 (0.68) SSTR4SSTR1SSTR2SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717161-A Nitrogen-containing saturated heterocyclic compound and preparation method, pharmaceutical composition and application thereof 广州费米子科技有限责任公司 2021-11-30 — — CN disclosed