Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947787 | 0.82 | MAPT (0.61) | CDC7CDK2MAPT | |
| SCHEMBL28687782 | 0.80 | ROCK1 (0.50) | CDC7CDK2ROCK1MAPTBIRC5 | |
| SCHEMBL28659589 | 0.80 | BIRC5 (0.57) | CDC7CDK2ROCK1MAPTMAP3K14 | |
| SCHEMBL28664985 | 0.80 | MAPT (0.50) | CDC7CDK2ROCK1MAPTBIRC5 | |
| SCHEMBL28930283 | 0.76 | CDC7 (0.53) | CDC7CDK2ROCK1MAPTMAP3K14 | |
| SCHEMBL28929918 | 0.76 | MAPT (0.51) | CDC7CDK2ROCK1MAPT | |
| SCHEMBL524138 | 0.75 | CDC7 (0.60) | CDC7CDK2ROCK1MAPTBIRC5 | |
| SCHEMBL31107087 | 0.75 | CDC7 (0.60) | CDC7CDK2ROCK1MAPTBIRC5 | |
| SCHEMBL29388549 | 0.75 | CDC7 (0.60) | CDC7CDK2ROCK1MAPTBIRC5 | |
| SCHEMBL29367108 | 0.73 | BIRC5 (0.67) | CDC7CDK2ROCK1MAPTBIRC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | claimed |
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |