Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 5/20 | 0.89 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.89 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034555 | 0.94 | KCNA3 (1.00) | KCNA3KCNN4MMP2LMNAL3MBTL1 | |
| SCHEMBL8667382 | 0.87 | KCNA3 (0.68) | KCNA3KCNN4MMP2HTR6CTSG | |
| SCHEMBL768700 | 0.85 | KCNN4 (0.67) | KCNA3KCNN4MMP2LMNAL3MBTL1 | |
| SCHEMBL28930398 | 0.85 | KCNA3 (0.70) | KCNA3KCNN4MMP2LMNANPSR1 | |
| SCHEMBL28665791 | 0.85 | KCNA3 (0.66) | KCNA3KCNN4MMP2LMNANPSR1 | |
| SCHEMBL14621111 | 0.84 | KCNA3 (0.68) | KCNA3KCNN4MMP2LMNAL3MBTL1 | |
| SCHEMBL1495922 | 0.83 | KCNN4 (0.64) | KCNA3KCNN4MMP2HTR6ALDH1A1 | |
| SCHEMBL3038159 | 0.81 | KCNA3 (0.78) | KCNA3KCNN4MMP2HTR6CTSG | |
| SCHEMBL28671140 | 0.80 | KCNA3 (0.60) | KCNA3KCNN4MMP2LMNANPSR1 | |
| SCHEMBL3045470 | 0.79 | KCNA3 (0.75) | KCNA3KCNN4MMP2L3MBTL1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735868-A | Synthesis method of pyrano [3,2-b ] indole-2-ketone compound | 西北工业大学 | 2021-12-03 | — | — | CN | claimed |
| CN-113735868-A | Synthesis method of pyrano [3,2-b ] indole-2-ketone compound | 西北工业大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113735868-A | Synthesis method of pyrano [3,2-b ] indole-2-ketone compound | 西北工业大学 | 2021-12-03 | — | — | CN | disclosed |