Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL2866824

C=CC(=O)OCC.C=CC(=O)OCCCl

nearest known ligand 0.57

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
HPGD P15428 1/20 0.57
ALDH1A1 P00352 7/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
HSD17B10 Q99714 2/20 0.52
THRB P10828 2/20 0.47
HCAR2 Q8TDS4 2/20 0.41
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14856 0.89
Ethyl Fumarate SCHEMBL17390691 0.88 HCAR2 (0.62) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL21268615 0.87
SCHEMBL15841395 0.87
Acrylic Acid Ethyl Ester SCHEMBL28273484 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL10930565 0.87
Acrylic Acid Ethyl Ester SCHEMBL10467352 0.87 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
Trimethylammonium SCHEMBL134540 0.86 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
Butadiene SCHEMBL28585464 0.85 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Ethyl Ester SCHEMBL8829513 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101981097-B Optical sheet, method for producing optical sheet, molded body, and method for producing molded body IDEMITSU KOSAN CO 2014-01-29 CN disclosed
CN-101981097-A Optical sheet, method for producing optical sheet, molded body, and method for producing molded body IDEMITSU KOSAN CO 2011-02-23 CN disclosed
US-7662905-B2 Copolycarbonate, copolycarbonate composition, and optical molded article obtained therefrom IDEMITSU KOSAN CO., LTD. (JP) 2010-02-16 US disclosed
CN-101467077-A Multilayer sheet for light reflection, reflector using same, lighting device, and liquid crystal display device IDEMITSU KOSAN CO (JP) 2009-06-24 CN disclosed
US-20080287610-A1 Copolycarbonate, Copolycarbonate Composition, and Optical molded Article Obtained Therefrom IDEMITSU KOSAN CO., LTD. (JP) 2008-11-20 US disclosed