Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.54 |
| ▸ | LCK | P06239 | 5/20 | 0.51 |
| ▸ | TEK | Q02763 | 5/20 | 0.51 |
| ▸ | FLT3 | P36888 | 7/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | KIF5B | P33176 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569236 | 1.00 | SRC (0.54) | SRCLCKTEKFLT3KDR | |
| SCHEMBL20351492 | 0.83 | SRC (0.56) | SRCLCKTEKFLT3KDR | |
| SCHEMBL28928813 | 0.82 | SRC (0.44) | SRCLCKFLT3KDRRET | |
| SCHEMBL30569271 | 0.82 | SRC (0.44) | SRCLCKFLT3KDRRET | |
| SCHEMBL30569256 | 0.82 | SRC (0.72) | SRCLCKTEKFLT3KDR | |
| SCHEMBL28667962 | 0.82 | SRC (0.72) | SRCLCKTEKFLT3KDR | |
| SCHEMBL20351773 | 0.81 | SRC (0.57) | SRCLCKTEKFLT3KDR | |
| SCHEMBL30569281 | 0.80 | SRC (0.63) | SRCLCKTEKFLT3KDR | |
| SCHEMBL28668000 | 0.80 | SRC (0.63) | SRCLCKTEKFLT3KDR | |
| SCHEMBL30569295 | 0.80 | RET (0.56) | SRCLCKTEKFLT3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-B | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |