Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 12/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 5/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | TEC | P42680 | 1/20 | 0.45 |
| ▸ | TXK | P42681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26359424 | 0.96 | IGF1R (0.49) | IGF1RTNK2JAK2JAK1 | |
| SCHEMBL14647470 | 0.90 | IGF1R (0.51) | IGF1RTNK2JAK2JAK1TYK2 | |
| SCHEMBL14647346 | 0.90 | IGF1R (0.51) | IGF1RTNK2JAK2JAK1TYK2 | |
| SCHEMBL593894 | 0.90 | IGF1R (0.51) | IGF1RTNK2 | |
| SCHEMBL15929297 | 0.90 | IGF1R (0.51) | IGF1RTNK2JAK2JAK1TYK2 | |
| SCHEMBL14654079 | 0.90 | IGF1R (0.51) | IGF1RTNK2JAK2JAK1TYK2 | |
| SCHEMBL30449939 | 0.85 | IGF1R (0.49) | IGF1RTNK2JAK2JAK1TYK2 | |
| SCHEMBL15929395 | 0.85 | TNK2 (0.48) | TNK2JAK2JAK1TYK2JAK3 | |
| SCHEMBL21050808 | 0.85 | IGF1R (0.49) | IGF1RTNK2JAK2JAK1 | |
| SCHEMBL28724598 | 0.85 | IGF1R (0.49) | IGF1RTNK2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111446-B | Heteroaryl compound with pharmaceutical activity | 上海度德医药科技有限公司 | 2021-11-30 | — | — | CN | disclosed |