SCHEMBL28669778

SCHEMBL28669778

Fc1ccc(Sc2[c]ccc(-c3noc(C(F)(F)F)n3)c2)cc1F

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 17/20 0.42
HDAC1 Q13547 10/20 0.42
HDAC5 Q9UQL6 2/20 0.42
HDAC8 Q9BY41 8/20 0.40
HDAC4 P56524 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28663157 0.88 HDAC6 (0.44) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28669491 0.86 HDAC6 (0.47) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28654901 0.86 HDAC6 (0.41) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28661333 0.86 HDAC6 (0.44) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28676799 0.86 HDAC6 (0.45) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28654906 0.85 HDAC6 (0.46) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28655776 0.85 HDAC6 (0.44) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28659250 0.83 NR1H4 (0.44) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28661491 0.83 HDAC6 (0.46) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL28663174 0.83 HDAC6 (0.48) HDAC6HDAC1HDAC5HDAC8HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784958-B Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2024-04-30 CN claimed
CN-113784958-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2021-12-10 CN claimed
CN-113784958-B Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2024-04-30 CN disclosed
CN-113784958-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2021-12-10 CN disclosed