Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | CTSG | P08311 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62288 | 0.96 | TYR (0.49) | TYRHPGDALOX5HTTPTGS2 | |
| SCHEMBL27820514 | 0.96 | TYR (0.49) | TYRHPGDALOX5HTTPTGS2 | |
| SCHEMBL28233596 | 0.94 | TYR (0.47) | TYRHPGDALOX5HTTPTGS2 | |
| Benzene SCHEMBL28669217 | 0.93 | TYR (0.46) | TYRHPGDALOX5HTTPTGS2 | |
| Pentadecane SCHEMBL27969639 | 0.93 | TYR (0.54) | TYRHPGDALOX5HTTPTGS2 | |
| Hexane SCHEMBL11772099 | 0.91 | TYR (0.57) | TYRALOX5HTTPTGS2MEN1 | |
| Hydroquinone SCHEMBL28192739 | 0.91 | TYR (0.53) | TYRHPGDALOX5HTTPTGS2 | |
| SCHEMBL29161135 | 0.91 | TYR (0.57) | TYRALOX5HTTPTGS2MEN1 | |
| SCHEMBL10932407 | 0.89 | TYR (0.59) | TYRALOX5HTTPTGS2MEN1 | |
| SCHEMBL2774201 | 0.89 | TYR (0.59) | TYRALOX5HTTPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117431289-A | Fish skin protein polypeptide for fresh-keeping of aquatic products, preparation method and fresh-keeping method thereof | 中国农业大学三亚研究院 | 2024-01-23 | — | — | CN | disclosed |
| CN-114246204-B | Fish fresh-keeping composition and preparation method and application thereof | 中国农业大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-113730352-B | Dimethicone emulsion and preparation method thereof | 南京海纳医药科技股份有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-114246204-A | Fish flesh preservation composition and preparation method and application thereof | 中国农业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113730352-A | Dimethicone emulsion and preparation method thereof | 南京海纳医药科技股份有限公司 | 2021-12-03 | — | — | CN | disclosed |