Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.66 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864683 | 0.84 | NOTUM (0.64) | CYP11B1CYP11B2NOTUMKCNH2RAB9A | |
| Oxazolidine SCHEMBL28243031 | 0.83 | NOTUM (0.51) | CYP11B1CYP11B2NOTUMKCNH2RAB9A | |
| SCHEMBL2123479 | 0.79 | NOTUM (1.00) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL4981360 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL12833921 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL24459722 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL1313626 | 0.79 | NOTUM (1.00) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL805128 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMKCNH2RAB9A | |
| SCHEMBL19261295 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 | |
| SCHEMBL101949 | 0.79 | NOTUM (0.68) | CYP11B1CYP11B2NOTUMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582937-B | Green preparation method of isoxazole compound participated in by water-soluble vitamin E | 浙江工业大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-113582937-A | Green preparation method of water-soluble vitamin E-involved isoxazole compound | 浙江工业大学 | 2021-11-02 | — | — | CN | disclosed |