SCHEMBL28670423

SCHEMBL28670423

FC(F)(F)n1ccnc1.N=S

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 0.42
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
CYP17A1 P05093 3/20 0.37
NFKB1 P19838 2/20 0.33
QPCT Q16769 1/20 0.33
HSD17B10 Q99714 1/20 0.33
QPCTL Q9NXS2 1/20 0.33
NR1I2 O75469 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TBXA2R P21731 2/20 0.33
CCKBR P32239 2/20 0.33
OPRK1 P41145 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KCNH2 Q12809 2/20 0.33
NR1H4 Q96RI1 2/20 0.33
MLNR O43193 1/20 0.33
TBXAS1 P24557 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420876 0.93
Methane SCHEMBL27749767 0.90 CYP19A1 (0.44) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
SCHEMBL28186226 0.90 CYP19A1 (0.44) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
Bromide SCHEMBL28997982 0.90 CYP19A1 (0.44) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
Ethane SCHEMBL28777304 0.88 CYP19A1 (0.43) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
Butane SCHEMBL27860005 0.82 CYP17A1 (0.42) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
Ethyl Chloride SCHEMBL28697836 0.80 CYP17A1 (0.41) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
Butane SCHEMBL28139289 0.77 CYP17A1 (0.40) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
SCHEMBL422418 0.73 CYP19A1 (0.43) CYP19A1CYP11B1CYP11B2CYP17A1NFKB1
SCHEMBL421431 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107180954-B Ultra-thin graphene lithium ion single battery and graphene lithium ion battery pack 张廷祥 2021-10-26 CN disclosed