Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687680 | 1.00 | MEN1 (0.34) | MEN1KMT2AMAPK1HCRTR2EPHX2 | |
| SCHEMBL28747502 | 0.83 | KMT2A (0.35) | MEN1KMT2AMAPK1EPHX2CACNA1H | |
| SCHEMBL15218631 | 0.82 | KMT2A (0.38) | MEN1KMT2AMAPK1CACNA1HDPP8 | |
| SCHEMBL3312164 | 0.82 | MEN1 (0.38) | MEN1KMT2AMAPK1HCRTR2EPHX2 | |
| SCHEMBL22482737 | 0.82 | MEN1 (0.38) | MEN1KMT2AMAPK1HCRTR2EPHX2 | |
| SCHEMBL29675255 | 0.82 | MEN1 (0.38) | MEN1KMT2AMAPK1HCRTR2EPHX2 | |
| SCHEMBL13330960 | 0.82 | MEN1 (0.38) | MEN1KMT2AMAPK1HCRTR2EPHX2 | |
| SCHEMBL3054113 | 0.74 | MEN1 (0.38) | MEN1KMT2AMAPK1EPHX2CACNA1H | |
| SCHEMBL25281434 | 0.74 | MEN1 (0.32) | MEN1KMT2AMAPK1 | |
| SCHEMBL22469824 | 0.74 | MEN1 (0.32) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |