SCHEMBL2867196

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861158	0.80	TTK (0.65)	MAPTSMN1; SMN2RAB9ATTKMAPK8
	SCHEMBL2864712	0.75	ITK (0.56)	KDM4EALDH1A1TTKKMT2AAURKA
	SCHEMBL2870192	0.74	TTK (0.50)	TTKMAPK8AURKAAURKBLRRK2
	SCHEMBL2866772	0.74	EPHX2 (0.52)	MAPTSMN1; SMN2RAB9AMAPK1KDM4E
	SCHEMBL8260089	0.74	TTK (0.69)	KDM4ETTKMAPK8KMT2AAURKA
	SCHEMBL1460668	0.71	MAP2K4 (0.49)	MAPTMAPK1TTKAURKAAURKB
	SCHEMBL5377699	0.71	AURKA (0.60)	MAPK1AURKALRRK2ITK
	SCHEMBL8251866	0.71	JAK2 (0.74)	RAB9AAURKANPC1LRRK2ITK
	SCHEMBL2567175	0.71	NTRK1 (0.53)	MAPK1TTKMAPK8AURKAAURKB
	SCHEMBL14514347	0.71	ITK (0.67)	MAPK1AURKALRRK2ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.