Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689145 | 0.82 | BTK (0.61) | BTKMEN1KMT2A | |
| SCHEMBL20572741 | 0.79 | BTK (0.61) | BTKCPT2CPT1A | |
| SCHEMBL16597622 | 0.79 | BTK (0.56) | BTKEGFRTEC | |
| SCHEMBL19203181 | 0.76 | BTK (0.70) | BTK | |
| SCHEMBL19202621 | 0.75 | BTK (0.59) | BTKEGFRTEC | |
| SCHEMBL19202386 | 0.74 | BTK (0.70) | BTKEGFRTEC | |
| SCHEMBL19202347 | 0.74 | BTK (0.70) | BTKEGFRTEC | |
| SCHEMBL19202381 | 0.74 | BTK (0.70) | BTKEGFRTEC | |
| SCHEMBL20573086 | 0.74 | BTK (0.74) | BTK | |
| SCHEMBL17983499 | 0.74 | BTK (0.44) | BTKEGFRTEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602818-B | Pyrazole fused ring derivatives, preparation method thereof and application thereof in treating cancer, inflammation and immune diseases | 北京诺诚健华医药科技有限公司 | 2021-12-21 | — | — | CN | disclosed |