Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226859 | 1.00 | SPHK1 (0.30) | SPHK1 | |
| SCHEMBL2316548 | 0.86 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL3207970 | 0.86 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL2844999 | 0.86 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL16053531 | 0.83 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL18938507 | 0.83 | SPHK1 (0.42) | SPHK1 | |
| SCHEMBL18938509 | 0.83 | SPHK1 (0.42) | SPHK1 | |
| SCHEMBL3213303 | 0.82 | — | — | |
| SCHEMBL3213291 | 0.82 | — | — | |
| SCHEMBL25331993 | 0.81 | PTPN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139876-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116302-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2008-10-02 | — | — | WO | disclosed |