Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865500 | 0.92 | JAK2 (0.55) | JAK2KCNH2 | |
| SCHEMBL2870510 | 0.89 | JAK2 (0.53) | JAK2 | |
| SCHEMBL2863289 | 0.89 | JAK2 (0.55) | JAK2KCNH2 | |
| SCHEMBL2872707 | 0.83 | JAK2 (0.56) | JAK2KCNH2 | |
| SCHEMBL2862718 | 0.83 | JAK2 (0.55) | JAK2KCNH2 | |
| SCHEMBL2862101 | 0.82 | JAK2 (0.48) | JAK2KCNH2 | |
| SCHEMBL2863405 | 0.82 | JAK2 (0.42) | JAK2 | |
| SCHEMBL3503042 | 0.82 | JAK2 (0.54) | JAK2KCNH2 | |
| SCHEMBL2865144 | 0.82 | JAK2 (0.54) | JAK2KCNH2 | |
| SCHEMBL2863313 | 0.82 | JAK2 (0.56) | JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200612-A1 | INHIBITORS OF JANUS KINASES | Merck Sharp & Dohme Corp. (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009035575-A1 | INHIBITORS OF JANUS KINASES | MERCK & CO., INC. (US) | 2009-03-19 | — | — | WO | claimed |