Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 18/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28687638 | 0.93 | SGK1 (0.57) | SGK1 | |
| SCHEMBL20699313 | 0.85 | SGK1 (0.59) | SGK1CDK2 | |
| SCHEMBL28689669 | 0.82 | SGK1 (0.46) | SGK1 | |
| SCHEMBL20699400 | 0.80 | SGK1 (0.43) | SGK1FGFR1FGFR2 | |
| Trifluoroacetic Acid SCHEMBL20699305 | 0.80 | SGK1 (0.56) | SGK1CDK2 | |
| SCHEMBL20699308 | 0.77 | SGK1 (0.55) | SGK1CDK2 | |
| SCHEMBL20699403 | 0.76 | JAK3 (0.49) | SGK1FGFR1FGFR2 | |
| SCHEMBL30161719 | 0.76 | JAK3 (0.49) | SGK1FGFR1FGFR2 | |
| Trifluoroacetic Acid SCHEMBL29607045 | 0.75 | SGK1 (0.42) | SGK1 | |
| SCHEMBL20699393 | 0.72 | SGK1 (0.40) | SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831326-A | Condensed heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2021-12-24 | — | — | CN | disclosed |